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Chunk #17 — Results — Cell type-specific gene expression in the 10x Genomics dataset

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Comprehensive analyses of RNA-seq and genome-wide data point to enrichment of neuronal cell type subsets in neuropsychiatric disorders.
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In the quality control of a randomized representative subset (n = 108,844) of the 10x Genomics dataset, 8408 cells and 6419 non-expressed genes were removed from further analyses (Figs. S1–S3). Altogether, the subset consisted of a matrix with 21,579 genes and 100,436 cells with 16 cell clusters (Tables S3, S4). All cell clusters were subsequently mapped to brain cell types by specifically expressed marker genes (Figure S4).