Chunk #16 — Methods — Cell type enrichment using LDSC

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Comprehensive analyses of RNA-seq and genome-wide data point to enrichment of neuronal cell type subsets in neuropsychiatric disorders.

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value associated with the most specific decile for each cell type as not all methods provide an enrichment score. Methods for MAGMA, DEPICT, and cell type enrichment analyses using additional mouse and human scRNA datasets are outlined in the Supplementary Methods.