Demographic variables for EA and AA cases were generally similar (Table S1). For the AA population, controls were less likely to be female. In the EA population, gender distributions between cases and controls were similar. Controls were much older than cases in both populations (mean age of cases: 18.0 (AA) and 19.3 (EA) vs. mean age of controls: 45.8 (AA) and 52.2 (EA), which should protect against cryptic disease in the control groups.
