Chunk #47 — 3. RXRs, Ethanol Metabolism, and Alcoholic Liver Disease

Source

Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease.

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This latter finding suggests that in alcoholic liver disease and ethanol metabolism, RXR regulation of GSTs expression may be important not only for conjugation of toxic metabolites to GSH but also for the protection against the deleterious effects of lipid peroxidation.