Table 1 shows the characteristics of the primary and replication samples. The primary (MOAFTS) sample consisted of young adult women aged 18–27 years from the general population. Rates of anhedonia (22%), MDD (18.4%) and abuse (9.4%) are representative of young female populations, and generalize to the full sample (including non-genotyped individuals). Not surprisingly, rates of anhedonia (cases: 63.9%, controls: 51.2%), MDD (cases: 59.9%, controls: 51.3%), and abuse (51.6% and 24% of cases and controls respectively endorsing at least one form of abuse) were considerably higher in CATS. Rates are high in the controls presumably because they were matched with the heroin dependent cases for neighborhood characteristics.
