First, we conducted univariate analyses between anhedonia, rs1049353 and childhood physical abuse. Childhood physical abuse was strongly associated with anhedonia [O.R. 2.75, 95% C.I. 1.78–4.24] – 40.8% of those with a history of childhood physical abuse reported anhedonia compared with 20% of those without a history of abuse. Genotype (rs1049353) was not associated with anhedonia [O.R. 0.82, 95% C.I. 0.61–1.10] or with exposure to childhood physical abuse [O.R. 1.26, 95% C.I. 0.83–1.92].
