Chunk #12 — Materials and Methods — Bioinformatic and Expression Analyses

Source

Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: a genome-wide association study.

Embedded

yes

Text

We evaluated the regulatory potential of replicated findings using the HaploReg v2 database,[33] the University of Chicago expression quantitative trait loci (eQTL) browser, and publically available Montgomery et al.[34] expression array and RNA sequencing data (see S1 Methods). We assessed replication of gene expression findings using Genevar [35]and publically available expression array data from the MuTHER resource[36] and Stranger et al.[37] (see S1 Methods).