To determine whether the cerebellar eGWAS captured variants implicated in complex diseases/traits, we compared the top 2,980 cerebellar eGWAS cisSNPs with the top disease/trait associated SNPs in the “Catalog of Published GWAS” [26], curated by the National Human Genome Research Institute (www.genome.gov/gwastudies). This catalog compiles weekly search results from all published GWAS of ≥100,000 SNPs where associations of p≤1.0E-05 are reported. The catalog accessed on 04/23/2011 had 5,272 entries. We restricted our search to those entries where the “SNPs” column had only one SNP with an rs number. Thus, haplotypes and variants without rs numbers were excluded. There were 5,101 entries after this exclusion, comprised of 4,248 unique SNPs and 433 unique diseases. One SNP may associate with >1 disease/trait and each disease/trait may have ≥1 associating SNP. This list was linked to the 2,980 top cerebellar cisSNPs by common rs numbers.
