We identified 2,980 cisSNP/transcript associations (2,596 unique SNPs, 746 unique probes and 686 unique genes) that achieved genome-wide significance within both the ADs and non–ADs analyses with q values<0.05. All 2,980 cisSNP/transcript associations achieved genome-wide significance with q<0.05 and pBonf<0.05 in the combined ADs+non–ADs analysis. We sought validation of these hits in the temporal cortex of 399 subjects who had WG-DASL whole transcriptome measurements and whole-genome genotypes. RNA extractions, QC, WG-DASL measurements, transcript level detections and association analyses were performed for these temporal cortex samples, in the same manner as that for the cerebellar samples. After appropriate QC, 2,685 of the 2,980 top cerebellar cisSNP/transcript associations remained detectable among the temporal cortex results (2,387 unique SNPs, 677 unique probes and 625 unique genes).
