Even after adjustment for covariates, a history of SI was associated with 1.42 – 2.22 odds of use and dependence of alcohol, nicotine and cannabis (Table 2). Associations with SA were even stronger, with odds-ratios ranging from 1.47 to 4.42. Early substance use was also associated with both SI and SA, even after adjustment for covariates (Odds Ratio – OR - ranging from 1.80 to 2.71).