and habituation to the environment, which suggests the absence of deficits in gross motor function or habituation learning. When tested on the rotarod, performance of all mice improved as a function of repeated trials (Fig. 4E). Three-way ANOVA showed a significant effect of trial [F(1.825, 29.19) = 37.74, P < 0.0001], but there was no effect of alcohol intake or genotype, and no interaction among the variables. These data indicate that there are no abnormalities in motor ability among the genotypes or alcohol intake conditions at this age.
