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Chunk #13 — Results — Firing in DMS Is Overly Active during Errant Responses after ACC Lesions.

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Anterior cingulate cortex is necessary for adaptation of action plans.
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These results suggest that reduced directional encoding contributes to longer latencies to inhibit behavior on correct trials and selection of incorrect behavior on error trials. Above, we focused on correct trials; here we plot average firing on errant STOP trials aligned to the presentation of the second light cue (Fig. 3 B and C) during sessions where there was at least one stop error in each response direction. As above, firing tracked the location of second light on correct trials, and significant directional signals emerged shortly after cue onset and prior to the SCRT (Fig. 3B; black tick marks prior to SCRT; t tests every 100 ms; P < 0.01) in the control group but not in the lesion group (Fig. 3C).