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Chunk #103 — Online Methods — 11. Predicting regulators active in each tissue / cell type / lineage

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Integrative analysis of 111 reference human epigenomes.
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We show all 84 motifs that were significantly enriched (log2>=1.5) in any enhancer modules, across the full set of 226 enhancer modules (Fig. S13a) and in the 101 modules in which they were significantly enriched (Extended Data 8a). Similarly, we show all 10 enriched motifs across the full set of 111 individual reference epigenomes (Fig. S13b) and specifically in the 15 enriched epigenomes (Fig. S13c). Lastly, we show all 19 enriched motifs across the full set of 17 tissue groups (Fig. S13d), and specifically within the 10 groups that showed significant enrichments (Fig. S13e).