For visualization of regulator-cell type links (Fig. 8), we compute edge weights between each cell type and motif using these motif-module enrichments. For each motif and cell type, we compute the sum across all modules of the product of the log2 motif enrichment and the value of the cell type within the module center (only consider the highly associated cell types by replacing values <0.7 with 0). We show all resulting edge weights of at least 1.5 and visualize the network using Cytoscape117.
