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Chunk #25 — RESULTS — Comparison of Our Results with Previous GWA Studies

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Genome-wide association study of bipolar disorder in European American and African American individuals.
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We further analyzed our results relative to one of the single previously published GWA studies (i.e., Baum et al., 2008) (15), which included about half of the probands and controls used in the present study, in addition to a replication sample that is independent of our sample (i.e., was collected in Germany). Several of the 88 SNPs with replicated association signals in the Baum et al. study (15) also show nominal evidence of association in the present study (Table S4), including a SNP in ANK3 (i.e., rs9804190). The extent to which this can be considered evidence for a consistent finding, however, is limited given the overlap between the samples used in the two studies.