paperKB
coga / coga-kb
Help
Sign in

Chunk #19 — MATERIALS AND METHODS — Zygosity Determination and Genotyping

Source
Can we identify genes for alcohol consumption in samples ascertained for heterogeneous purposes?
Embedded
yes

Text

The various genome scans were integrated using the custom 'pedtool' software. The input to this integration consisted of (a) the raw data, (b) a list of target markers (those from different genotyping labs were kept distinct), (c) cM positions using an integrated genetic map based on NCBI build 35.1 (Duffy, 2006), and (d) a set of data-correction rules, derived from earlier cleaning of the component genome scans, that code for corrections to assumed pedigree structure and the dropping of bad DNA samples.