from both preclinical and clinical perspectives. This will be followed by a compilation of our findings with the P rat as it pertains to innate differences in gene and/or protein expression, relative to its NP counterpart, as well as ethanol’s modulation of gene and/or protein expression in subregions of the mesocorticolimbic reward circuitry. This minireview will then be concluded with some closing thoughts on some limitations observed in the existing literature.
