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Chunk #29 — Discussion

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Genome-wide and candidate gene association study of cigarette smoking behaviors.
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five Transient Receptor Family Potential (TRP) subfamily members and nicotine related behaviors in the canonical (this study Table 2, [59] Table 1, and [79]) and vanilloid subfamilies (this study Table 3, and Saccone et al., 2007, Supplementary Material [50]). Recently, Gu et al., 2005 [80] have shown that vanilloid subfamily members are expressed in the lung and are responsible for the pulmonary chemoreflex response, suggesting further study of these TRP subfamilies and their potential role in smoking behavior and downstream consequences may be fruitful.