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Chunk #3 — Sensation Seeking as Intermediate Phenotype Linking Genetic Influences to Alcohol Use

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The associations between polygenic risk, sensation seeking, social support, and alcohol use in adulthood.
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seeking beyond adolescence (Evans-Polce et al., 2018) and between emerging adulthood and middle adulthood (Zuckerman et al., 1978). The association between sensation seeking and binge drinking has also been found to decline across ages 18 to 30 (Evans-Polce et al., 2018). It remains unknown whether the associations between sensation seeking and alcohol use outcomes continue to decline beyond emerging adulthood or are similar between emerging adults and middle-aged adults.