However, very few studies have explicitly investigated the role of sensation seeking in mediating the association between genetic factors and alcohol use. Using data from the Finnish Twin Cohort, Li et al. (2017) showed that sensation seeking partially mediated the association between genetic risk for alcohol dependence, measured as a genome-wide polygenic score (GPS), and alcohol use problems at age 16. In a sample of college students, sensation seeking also partially mediated the association between genetic predispositions toward risky behaviors and alcohol consumption (Ksinan, et al., 2019). Notably, previous studies on the mediating role of sensation seeking have primarily focused on adolescents or emerging adults. Limited research has examined whether the role of sensation seeking in alcohol use vary across a broader range of ages across adulthood. However, there is some evidence of a general decline in levels of sensation seeking beyond adolescence (Evans-Polce et al., 2018) and between emerging adulthood and middle adulthood (Zuckerman et al., 1978). The association between sensation seeking and binge drinking has also been found to decline across ages 18 to 30 (Evans-Polce et al.,
