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Chunk #11 — Materials and Methods — Measures — LBC1921 & LBC1936

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Genome-wide association uncovers shared genetic effects among personality traits and mood states.
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Personality was measured by the International Personality Item Pool Big-Five 50-item inventory (Goldberg 1999), consisting of 10 items for each trait. Anxiety and depression symptoms were quantified using the Hospital Anxiety Depression Scale (Zigmond and Snaith 1983), containing seven items each for anxiety and depression, the total score giving a general measure of psychological distress.