In the second gender separated analysis 49 female participants (31 HR and 18 LR) were compared. The groups did not differ with respect to socioeconomic status (SES), or ICV though the females, similar to all HR offspring, were significantly more likely to have been exposed to prenatal alcohol, drugs and cigarettes (Table 1). For the females, differences by risk group membership were seen for the right fusiform (p = 0.019), and for two cerebellar regions. Lobe 8 (left) showed a significant reduction in volume (p=0.006) as did the cerebellar crus I (p=0.001) (Figure 3, Table 4).
