The qEEG patterns and abnormalities depend significantly on whether the subject is still currently using, the chronicity of use, and the current stage of withdrawal or protracted abstinence. A neurofeedback protocol selected for an individual client with SUD should be directly related to the level of current substance use or abstinence, especially in such classes of drugs as heroin, where the withdrawal syndrome results in substantial physiological manifestations including transient qEEG changes.