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Chunk #16 — Materials and Methods — Statistical Analysis

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Further development of a neurobehavioral profile of fetal alcohol spectrum disorders.
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conditional response means (CRMs) are interpreted to substantively characterize those within each profile. CRMs indicate the mean value for an observed variable within a profile. All models were estimated using MPlus (Muthén and Muthén, 2006). Three LPAs were conducted with the following a priori subject comparisons: (1) subjects with AE and a diagnosis of FAS and non-exposed controls, (2) subjects with AE without FAS and non-exposed controls, and (3) subjects with AE (with and without FAS), and non-exposed subjects with ADHD. The same neuropsychological variables were included in all analyses and 1-, 2-, and 3-class solutions were evaluated. With these analyses, we aimed to determine whether our neuropsychological data could distinguish alcohol-exposed subjects from controls and whether this profile was specific to the effects of heavy prenatal alcohol exposure compared to a clinical contrast group. Logistic regression analyses with classification tables were evaluated subsequent to the LPAs. The profiles were crossed with the target comparison groups (e.g., AE vs. CON) to evaluate how well the classes predicted group membership.