Chunk #27 — Long-range connectivity — Are white matter diseases more likely to specifically trigger psychosis, or is this feature common whatever the type of encephalopathy?
In many neurodegenerative diseases, eg, metabolic or vascular diseases, psychosis can precede dementia. Some WM. diseases also evolve toward a dementia. Thus, it is questionable whether WM diseases have a selective role in provoking psychosis, or whether psychosis is just an early reaction to a nonspecific encephalopathy. Indeed, the comparison with Alzheimer's disease shows
