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Chunk #55 — Online Methods — Tissue specific enrichment of overlap of histone marks

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Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.
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Two methods were used to test for enrichment of the 97 signals of association with lung function for H3K4me1 and H3K4me3 histone marks in up to 127 different tissue and cell types from the ENCODE and RoadMap projects39.