For other clusters of risk factors for which we approximated the joint effects assuming independence, dietary risk factors and physical inactivity were responsible for the largest disease burden: 10·0% (9·2–10·8) of global DALYs in 2010. Of the individual dietary risk factors, the largest attributable burden in 2010 was associated with diets low in fruits (4·9 million [3·8 million to 5·9 million] deaths and 4·2% [3·3–5·0] of global DALYs), followed by diets high in sodium (4·0 million [3·4 million to 4·6 million]; 2·5% [1·7–3·3]), low in nuts and seeds (2·5 million [1·6 million to 3·2 million]; 2·1% [1·3–2·7]), low in whole grains (1·7 million [1·3 million to 2·1 million]; 1·6% [1·3–1·9]), low in vegetables (1·8 million [1·2 million to 2·3 million]; 1·5% [1·0–2·1]), and low in seafood omega-3 fatty acids (1·4 million [1·0 million to 1·8 million]; 1·1% [0·8–1·5]). Our sensitivity analysis of omega-3 fatty acids using relative risks from randomised trials reduced the attributable burden by more than half, to 0·6 million (–0·6 million to 1·7 million) deaths, and 0·5% (−0·5 to 1·4) of global DALYs in 2010. Physical inactivity
