Chunk #14 — MATERIALS AND METHODS — Phenotypic Cluster Analysis

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Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis.

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Based on the clusters’ lifetime prevalence of substance use and psychiatric disorders (Table II) and cocaine-related features (Table III), we named Group 2 the “moderate cocaine use group,” Group 3 the “late-onset heavy cocaine use group,” Group 4 the “heavy cocaine use, infrequent intravenous injection group,” and Group 5 the “early-onset, heavy cocaine use, high comorbidity group.”