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Chunk #13 — MATERIALS AND METHODS — Phenotypic Cluster Analysis

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Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis.
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We identified five mutually exclusive clusters. As shown in Table I, the groups differed significantly on age, sex, race, education, and marital status. Specifically, Groups 2–5 (the cocaine use clusters) included significantly more men than women and were less educated than Group 1 (the “non-cocaine use group”). Group 5 had the lowest level of education and the fewest married members and included a significantly higher proportion of EAs than Groups 2–4. Groups 3 and 4 included a significantly higher proportion of AAs than the other three groups.