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Chunk #7 — PART 1: OVERVIEW OF DATA COLLECTION — Wave 1: Initial ascertainment and assessment

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The collaborative study on the genetics of alcoholism: Sample and clinical data.
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In this first data collection wave, 9325 adults aged 18 or older, and 1333 children aged 6–17 in 2246 families were assessed. Interviews occurred from 1991 to 1999 (most from 1991 to 1996). Participants were administered the SSAGA in person, although telephone assessments were conducted when transportation difficulties or distance precluded an in‐person visit. 11 Tables 2 (adults) and 3 (children) summarize the participant characteristics, separately for the probands, their relatives, and participants in comparison families. A few points merit comment here. Probands and their family members are racially/ethnically diverse, middle aged, with an unsurprising predominance of men in the proband sample (74.8%) which derived from treatment programs, but a higher proportion of women among the relatives (59%). By definition, probands were affected with AUD; as expected, the prevalence of Alcohol Dependence among their relatives was much higher than that observed among comparison family participants (34.6% vs. 16.6%). There is considerable addiction comorbidity among the probands, particularly for cannabis and cocaine where 44.9% and 48.4% met dependence criteria respectively. Comorbidity with other substance dependence is less pronounced among their relatives,