the AUDIT-C (e.g., rg = 0.52, p = 2.40e-42) (Kranzler et al., 2019; Marees et al., 2019), while another study found that polygenic risk scores (PRS) for past week alcohol consumption predicted a modest but significant amount of variance in AUD (e.g., R2 = 0.56%; Johnson et al., 2019), suggesting that the genetic correspondence between recent consumption and dependence may be complicated by several factors, including the characteristics of the sample, and the nature of the assessment (e.g., alcohol quantity vs. frequency (Marees et al., 2019)).
