and both groups spent less time on the floor when it was paired with saline (GRID-group). Mean activity during each 5-min ethanol (CS+) and saline (CS−) conditioning trial are depicted in Fig. 9B. Activity on saline trials was decreased across trials in both groups of mice (saline- and LPS-pretreated) [F(3, 147) = 8.8, p < .001, effect of trial], with slightly reduced activity in LPS-pretreated mice [F(3, 147) = 5.9, p < .05, effect of pre-treatment]. Ethanol produced an increase in activity relative to saline in both groups of mice. However, this stimulation of motor activity was not affected by LPS treatment.
