The PGC-PTSD21 Freeze 3 data collection includes 1,307,247 individuals from 88 studies (Supplementary Table 1). Data in this freeze were assembled from three primary sources (Fig. 1a): PTSD studies based on clinician administered or self-reported instruments (Freeze 2.511,12 plus subsequently collected studies), MVP release 3 GWASs utilizing the Posttraumatic Stress Disorder Checklist (PCL for DSM-IV)13, and 10 biobank studies with electronic health record (EHR)-derived PTSD status. We included 95 GWASs, including EA (n = 1,222,882; effective sample size (neff) = 641,533), AA (n = 51,034; neff = 42,804) and LAT (n = 7,017; neff = 6,530) participants (Supplementary Table 2).
