will need to account for fluctuations in gonadal hormones, and possibly pubertal timing (Marceau, Ram, Houts, Grimm, & Susman, 2011), to isolate contributing factors for FRN differences across the sexes. Finally, we observed a sex effect in our source analyses, specific to the subgenual ACC, with males generally showing greater activation in this region compared to females, irrespective of feedback type. Subgenual ACC functioning has been linked tomood disorders (Drevets, Savitz, &Trimble, 2008) with some effects specifically related to hormone regulation among women with a history of major depression (Holsen et al., 2011). It will be interesting to know whether the sex difference we observed in subgenual ACC activation for reward processing tracks aspects of depressive symptomatology, particularly those related to hedonic capacity.
