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Chunk #23 — Results — Association between EEG functional connectivity and AUD and PTSD symptoms in trauma-exposed participants

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Childhood trauma is associated with developmental trajectories of EEG coherence, alcohol-related outcomes, and PTSD symptoms.
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Results of LGCMs estimating the associations between intercept and slope of alpha EEGc and subsequent AUDsx and PTSDsx in male and female trauma-exposed participants are displayed in Table 4. We found that intercept of LFC alpha EEGc (FZ-CZ--F3-C3) was positively associated with both AUDsx (ß = 0.53, p < 0.001) and PTSDsx (ß = 2.65, p < 0.001) in trauma-exposed females, suggesting that greater initial values of EEGc were associated with higher levels of PTSD and AUD symptoms. There were no FZ-CZ--F3-C3 intercept or slope associations with AUDsx or PTSDsx observed in trauma-exposed males. For our measure of RFC alpha EEGc (FZ-CZ--F4-C4), we found that intercept was significantly positively associated with both AUDsx (ß = 4.10, p < 0.001) and PTSDsx (ß = 2.47, p < 0.001) in males. In females, slope of RFC alpha EEGc (FZ-CZ--F4-C4) was negatively associated with AUDsx (ß = −3.16, p = 0.002) and PTSDsx (ß = −5.19, p = 0.001), suggesting that diminished growth of EEGc was associated with greater AUDsx and PTSDsx. For PFI alpha EEGc (F8-F4--F7-F3), intercept was significantly positively associated with