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Chunk #12 — Method — Analytic strategy

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Alcohol use polygenic risk score, social support, and alcohol use among European American and African American adults.
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as additional predictors to the regression model (Model 3). We also examined potential gene-environment correlations (rGE) by testing correlations between alc-PRS and family/friend support. Significant rGE were accounted for in our models testing G×E effects by specifying alc-PRS and family/friend support to be correlated using the “WITH” command in Mplus. To check the robustness of significant G×E effects, we conducted additional analysis that included alc-PRS × covariate as well as social support × covariate interaction terms in the regression model to further account for potential confounding effects, following recommendations by Keller (2014).