rats (N. E. Badia-Elder, personal communication). In a study examining P versus NP rats (Froehlich et al. 1988), P rats were less affected, as indicated by a more modest decrease in saccharin intake following conditioning with a moderate dose (1.0 g/kg) of alcohol than NP rats, and showed a transient facilitation of saccharin intake after conditioning with a low dose (0.25 g/kg) of alcohol, whereas NP rats displayed no effect at the latter dose. Similarly, sP rats were not affected by conditioning with a 1.0 g/kg dose of alcohol, whereas sNP rats displayed a strong CTA to saccharin after conditioning with this dose (Brunetti et al. 2002). Similar findings have been reported for the UChB versus UChA rat lines, with the high alcohol-drinking UChB line displaying a very low CTA to saccharin after conditioning with either alcohol (Quintanilla et al. 2001) or alcohol’s first metabolite, acetaldehyde (Quintanilla et al. 2002) compared with the low alcohol-drinking UChA line. When the selectively bred high alcohol-preferring (HAP-1 and HAP-2 replicates) mice and their low alcohol-preferring (LAP-1 and LAP-2 replicates) counterparts were examined, it was found that, as with the rat lines, HAP-1 and HAP-2 mice showed a significantly lesser CTA to sodium chloride
