a pronounced conditioned place preference (CPP) (Ciccocioppo et al. 1999). It should be noted that the msP line has no direct comparator line, selected for low drinking—nonetheless, the direction of the effect was opposite to that seen in the P and NP lines. Another behavioral index of the subjective effects of alcohol is the conditioned taste aversion (CTA) assay. Drinking of a novel flavored solution (usually a sweet solution or a weak saline solution) is paired with an injection of alcohol. If selectively bred high alcohol-consuming lines of rats self-administer greater amounts of alcohol than their low alcohol-consuming counterparts because of a low response to alcohol’s aversive properties, it would be predicted that the high drinking lines would display a lower CTA for a flavored solution when conditioned (i.e., preceded by) a moderate dose of alcohol. Such were the findings in a study examining HAD-2 and LAD-2 rats, with HAD-2 rats displaying a low CTA to saccharin compared with LAD-2 rats (N. E. Badia-Elder, personal communication). In a study examining P versus NP rats (Froehlich et al. 1988), P rats were less affected, as indicated by a more modest decrease in saccharin intake following conditioning with a moderate dose (1.0
