participated in the study design and developed the food-frequency questionnaire; IL reviewed pathological material to confirm the diagnosis of lung cancer and histologic classification; FP designed and developed the database and portal for the study; MC and MRu coordinated all field activities and developed related readable forms and infrastructures for data processing; BM and BA participated in the design of the laboratory component of the study, and directed laboratory procedures for the subjects' biospecimen collection, processing, storage, and shipments; AC participated in the design of the study, was responsible for all laboratory activities, and developed the Standard Operating Procedures for the laboratory; MT and SW participated in the study design, management and analytical strategies, and oversaw all steps of the study; ACP participated in the design and management of the study, and designed and implemented all the infrastructures for population controls' enrollment, and related weekly reports and quality control procedures; NEC was responsible for the conception and design of the study, and oversaw all aspects of the study activities, patients recruitment, funding, and interpretation of the data; PAB contributed to the study design, analytical strategy, and management, and was the ultimate responsible for all study activities at EPOCA, University of