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Chunk #16 — Methods — Anatomical likelihood estimation

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A coordinate-based meta-analysis of white matter alterations in patients with alcohol use disorder.
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The meta-analytical approach of anatomical likelihood estimation follows the principles of activation likelihood estimation (ALE) [37, 38], whereby the above-chance convergence among the reported coordinates of the individual studies gets detected. To ensure adequate power, the inclusion of 17–20 studies is recommended [28, 39].