of injury to particular white matter structures undoubtedly varied widely. For example, Benson et al. (2007)10 examined the integrity of whole-brain white matter of twenty patients with TAI using a histogram analysis and demonstrated that the distribution of white matter fractional anisotropy (i.e. measure of the directionality of water diffusion along axons) for individual patients was significantly more variable than the distribution for healthy controls. Variability of white matter integrity in various interhemispheric structures, may in part, explain how interhemispheric connectivity can be reduced without reducing cognitive or functional ability, as it is possible certain patients suffered damage to the CC and subsequently rerouted neuronal signal between hippocampi through less direct but more intact commissural fibers (i.e., posterior cingulate, hippocampal commissure), thereby lowering their degree of interhemispheric hippocampal connectivity, but maintaining enough contralateral connectivity to approximate the desired behavior.
