ranked of the candidate genes (Huntingtin, HTT) was included in the candidate list because mood disorders are characteristic of presymptomatic carriers of the Huntington's disease trinucleotide repeat polymorphisms.31 HTT ranked in the top 0.7% of all genes; the SNP showing highest individual association within the gene is rs363099 (also known as rs4690074, P=4.7 E−04, OR=0.86, MAF=0.31) located in exon 29, 85 kb from the exon 1 CAG repeat.
