Gene-based tests identified seven genes associated with BD in the CADD sample. However, neither the genes nor pathways identified as marginally overrepresented in the CADD GWAS results showed evidence of replicable low-p-values in either the MCTFR or SAGE samples. Taken together, these findings suggest that discoverable effects of common SNPs underlie the genetic architecture of BD, although better-powered studies are required to identify the associated loci.
