The differences between the SZ and HC groups in age and z‐scores of each neurocognitive test were examined by independent‐samples t test. Gender difference between the groups was assessed using the chi‐square test. Using Pearson's correlation test, correlation of FA of each callosal segment with age was assessed in the HC groups, and correlation of FA of each callosal segment with age and equivalent doses of antipsychotics was assessed in the SZ group. Correlation of the z‐score of neuropsychological tests with equivalent doses of antipsychotics was also assessed using Pearson's correlation test in the SZ group. In the above analyses, the statistical significance level was set at p < 0.05. Stepwise multiple regression analysis was performed, with the z‐scores of list learning test, digit sequencing test, token motor test, verbal fluency test, symbol coding test, the Tower of London test, and the composite score as dependent variables, and the FA of callosal fibers in each segment as independent variables to investigate the relationship between the FA and cognitive function in all subjects. The statistical significance level was set at p