Thirty-eight right-handed healthy social drinkers between the ages of 21 and 35 were recruited. They endorsed drinking at least one to three drinks per week and reported at least one incidence of drunkenness over the previous month. No participants were alcohol dependent or had a maternal history of alcoholism. They had to be in good health, without medications (licit or illicit), and have a normal sense of smell. Smokers enrolled if they could abstain from tobacco smoking for four hours without nicotine withdrawal. All participants voluntarily signed informed consent statements approved by the Indiana University institutional review board and received $150 for completion of study. Of the recruited sample, 30 completed the study. Participants who completed the study did not differ from non-completers on any demographic variables (p-values = 0.19-0.86), drinking-related problems (AUDIT total score, p = 0.57), or family histories of alcohol problems (p = 0.53). Three subjects whose head motion during functional imaging exceeded peak-to-peak translations of 2 mm and rotations of 2 deg were excluded from further analyses, resulting in a final sample of n = 27 (Table 1).
