PAU-PRS was associated with reduced left frontal pole gray matter volume (standardized β= −0.054, r2=0.003, pfdr=0.031; Figure 1; Table 1). PAU-PRS was also associated with greater right supramarginal gyrus cortical thickness (standardized β=0.009, r2=0.001, pfdr=0.045; Figure 1; Table 1). Cognition as well as externalizing problems were not associated with frontal pole gray matter volume or supramarginal gyrus cortical thickness (All p > .21; Supplemental Table 4).
