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Chunk #16 — Results — Early onset alcohol use and risk for self-harm

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Early onset alcohol use and self-harm: a discordant twin analysis.
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The mean discordance within twin pairs for EAU was 3.61 years. Within the discordant pairs (Table 3), the twin reporting EAU was at nearly three-fold increased likelihood of also reporting NSSI (OR=2.75, 95% CI: 1.65-4.59, p<.01) relative to their later onset co-twin. A significant elevation in odds for SA was also observed (OR=2.40, 95% CI: 1.31-4.38, p<.05). When adjusting for covariates, EAU resulted in a nearly eight-fold increased likelihood of NSSI (OR=7.62, 95% CI: 2.58-22.54, p<.01) and an almost four-fold increased likelihood of SA (OR=3.72, 95% CI: 1.19-11.64, p<.05), although the confidence limits around these point estimates were wide. Only anhedonia emerged as a significant covariate for SA. All parameter estimates and test statistics are reported in Supplemental Table 1.