Two SNPs in SLC6A3 (rs27048, p = 0.042, OR = 0.68; rs10052016, p = 0.00055, OR = 1.33) were associated with the dichotomous phenotype of AD. Within the same gene, we also identified an association between the common allele (C) of another SNP (rs6350, p = 0.0021, β = −0.36) and AD symptoms. Lind and colleagues (2009) found association of the same allele in rs6350 with problem drinking in a Finnish population.
