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Chunk #47 — SEX DIFFERENCES IN MOLECULAR GENETIC STUDIES — GWAS/SNPs

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Using the tools of genetic epidemiology to understand sex differences in neuropsychiatric disorders.
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females; however, when considering differing allelic effects between genders, their method offers substantial gains in power. Clearly, additional methodological investigation in this area is warranted. Finally, the Neale Lab (http://www.nealelab.is) at the Broad Institute has published publicly available GWAS summary statistics for the phenotypes in the UK Biobank (http://www.ukbiobank.ac.uk), for males and females combined and separately in an online repository (http://www.nealelab.is/uk-biobank) in order to allow researchers to examine sex‐specific associations. This resource should facilitate future comparisons of GWAS findings, SNP‐based heritability and PRS between males and females for a variety of psychiatrically relevant phenotypes.