In the pressing task, PAC was markedly modulated around movement transitions. Figure 5B illustrates the averaged dynamics of PAC across the first three periods as resulting from aligning data with the cortical movement transition point #1 (defining the transition between premovement onset and force build-up, left), and the last three periods as resulting from aligning data with the cortical movement transition point #4 (defining the transition between force release and press offset, right). As shown in Fig. 5B, close to the press onset, PAC appeared to decrease from a brief maximum, reaching a minimum before rising again (also evident in Fig. 4). Alignment with the transition at release offset revealed a PAC motif similar to that at press onset (Fig. 5B, right). Two-way mixed ANOVA on group and period showed significant main effects for the factors group [F(1,37) = 5.57, P = 0.024] and period [F(4,148) = 4.72, P = 0.001]. Because there was no group × period interaction effect [F(4,148) = 1.08, P = 0.369], PAC was not modulated differently between patients and controls. To investigate the effect of
